Búsqueda | Biblioteca Virtual en Salud Odontología. Uruguay

1.

PD-L1-PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection.

Perry, Joseph A; Shallberg, Lindsey; Clark, Joseph T; Gullicksrud, Jodi A; DeLong, Jonathan H; Douglas, Bonnie B; Hart, Andrew P; Lanzar, Zachary; O'Dea, Keenan; Konradt, Christoph; Park, Jeongho; Kuchroo, Juhi R; Grubaugh, Daniel; Zaretsky, Arielle Glatman; Brodsky, Igor E; Malefyt, Rene de Waal; Christian, David A; Sharpe, Arlene H; Hunter, Christopher A.

Nat Immunol ; 23(5): 743-756, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-35437326

2.

The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade.

Cucolo, Lisa; Chen, Qingzhou; Qiu, Jingya; Yu, Yongjun; Klapholz, Max; Budinich, Krista A; Zhang, Zhaojun; Shao, Yue; Brodsky, Igor E; Jordan, Martha S; Gilliland, D Gary; Zhang, Nancy R; Shi, Junwei; Minn, Andy J.

Immunity ; 55(4): 671-685.e10, 2022 04 12.

Artículo en Inglés | MEDLINE | ID: mdl-35417675

3.

Microbiota-Dependent Sequelae of Acute Infection Compromise Tissue-Specific Immunity.

Fonseca, Denise Morais da; Hand, Timothy W; Han, Seong-Ji; Gerner, Michael Y; Glatman Zaretsky, Arielle; Byrd, Allyson L; Harrison, Oliver J; Ortiz, Alexandra M; Quinones, Mariam; Trinchieri, Giorgio; Brenchley, Jason M; Brodsky, Igor E; Germain, Ronald N; Randolph, Gwendalyn J; Belkaid, Yasmine.

Cell ; 163(2): 354-66, 2015 Oct 08.

Artículo en Inglés | MEDLINE | ID: mdl-26451485

4.

Collab or Cancel? Bacterial Influencers of Inflammasome Signaling.

Herrmann, Beatrice I; Grayczyk, James P; Brodsky, Igor E.

Annu Rev Microbiol ; 77: 451-477, 2023 09 15.

Artículo en Inglés | MEDLINE | ID: mdl-37713455

5.

Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock.

Mandal, Pratyusha; Feng, Yanjun; Lyons, John D; Berger, Scott B; Otani, Shunsuke; DeLaney, Alexandra; Tharp, Gregory K; Maner-Smith, Kristal; Burd, Eileen M; Schaeffer, Michelle; Hoffman, Sandra; Capriotti, Carol; Roback, Linda; Young, Cedrick B; Liang, Zhe; Ortlund, Eric A; DiPaolo, Nelson C; Bosinger, Steven; Bertin, John; Gough, Peter J; Brodsky, Igor E; Coopersmith, Craig M; Shayakhmetov, Dmitry M; Mocarski, Edward S.

Immunity ; 49(1): 42-55.e6, 2018 07 17.

Artículo en Inglés | MEDLINE | ID: mdl-30021146

6.

NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8.

Rauch, Isabella; Deets, Katherine A; Ji, Daisy X; von Moltke, Jakob; Tenthorey, Jeannette L; Lee, Angus Y; Philip, Naomi H; Ayres, Janelle S; Brodsky, Igor E; Gronert, Karsten; Vance, Russell E.

Immunity ; 46(4): 649-659, 2017 04 18.

Artículo en Inglés | MEDLINE | ID: mdl-28410991

7.

White Adipose Tissue Is a Reservoir for Memory T Cells and Promotes Protective Memory Responses to Infection.

Han, Seong-Ji; Glatman Zaretsky, Arielle; Andrade-Oliveira, Vinicius; Collins, Nicholas; Dzutsev, Amiran; Shaik, Jahangheer; Morais da Fonseca, Denise; Harrison, Oliver J; Tamoutounour, Samira; Byrd, Allyson L; Smelkinson, Margery; Bouladoux, Nicolas; Bliska, James B; Brenchley, Jason M; Brodsky, Igor E; Belkaid, Yasmine.

Immunity ; 47(6): 1154-1168.e6, 2017 12 19.

Artículo en Inglés | MEDLINE | ID: mdl-29221731

8.

Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA.

Mowel, Walter K; McCright, Sam J; Kotzin, Jonathan J; Collet, Magalie A; Uyar, Asli; Chen, Xin; DeLaney, Alexandra; Spencer, Sean P; Virtue, Anthony T; Yang, EnJun; Villarino, Alejandro; Kurachi, Makoto; Dunagin, Margaret C; Pritchard, Gretchen Harms; Stein, Judith; Hughes, Cynthia; Fonseca-Pereira, Diogo; Veiga-Fernandes, Henrique; Raj, Arjun; Kambayashi, Taku; Brodsky, Igor E; O'Shea, John J; Wherry, E John; Goff, Loyal A; Rinn, John L; Williams, Adam; Flavell, Richard A; Henao-Mejia, Jorge.

Immunity ; 47(3): 435-449.e8, 2017 09 19.

Artículo en Inglés | MEDLINE | ID: mdl-28930659

9.

TNF licenses macrophages to undergo rapid caspase-1, -11, and -8-mediated cell death that restricts Legionella pneumophila infection.

Pollock, Tzvi Y; Vázquez Marrero, Víctor R; Brodsky, Igor E; Shin, Sunny.

PLoS Pathog ; 19(6): e1010767, 2023 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-37279255

10.

Human NAIP/NLRC4 and NLRP3 inflammasomes detect Salmonella type III secretion system activities to restrict intracellular bacterial replication.

Naseer, Nawar; Egan, Marisa S; Reyes Ruiz, Valeria M; Scott, William P; Hunter, Emma N; Demissie, Tabitha; Rauch, Isabella; Brodsky, Igor E; Shin, Sunny.

PLoS Pathog ; 18(1): e1009718, 2022 01.

Artículo en Inglés | MEDLINE | ID: mdl-35073381

11.

RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling.

Chen, Kaiwen W; Demarco, Benjamin; Ramos, Saray; Heilig, Rosalie; Goris, Michiel; Grayczyk, James P; Assenmacher, Charles-Antoine; Radaelli, Enrico; Joannas, Leonel D; Henao-Mejia, Jorge; Tacchini-Cottier, Fabienne; Brodsky, Igor E; Broz, Petr.

Proc Natl Acad Sci U S A ; 118(28)2021 07 13.

Artículo en Inglés | MEDLINE | ID: mdl-34260403

12.

The intestinal parasite Cryptosporidium is controlled by an enterocyte intrinsic inflammasome that depends on NLRP6.

Sateriale, Adam; Gullicksrud, Jodi A; Engiles, Julie B; McLeod, Briana I; Kugler, Emily M; Henao-Mejia, Jorge; Zhou, Ting; Ring, Aaron M; Brodsky, Igor E; Hunter, Christopher A; Striepen, Boris.

Proc Natl Acad Sci U S A ; 118(2)2021 01 12.

Artículo en Inglés | MEDLINE | ID: mdl-33372132

13.

Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection.

Bjanes, Elisabet; Sillas, Reyna Garcia; Matsuda, Rina; Demarco, Benjamin; Fettrelet, Timothée; DeLaney, Alexandra A; Kornfeld, Opher S; Lee, Bettina L; Rodríguez López, Eric M; Grubaugh, Daniel; Wynosky-Dolfi, Meghan A; Philip, Naomi H; Krespan, Elise; Tovar, Dorothy; Joannas, Leonel; Beiting, Daniel P; Henao-Mejia, Jorge; Schaefer, Brian C; Chen, Kaiwen W; Broz, Petr; Brodsky, Igor E.

PLoS Pathog ; 17(10): e1009967, 2021 10.

Artículo en Inglés | MEDLINE | ID: mdl-34648590

14.

Position-Specific Secondary Acylation Determines Detection of Lipid A by Murine TLR4 and Caspase-11.

Harberts, Erin M; Grubaugh, Daniel; Akuma, Daniel C; Shin, Sunny; Ernst, Robert K; Brodsky, Igor E.

Infect Immun ; 90(8): e0020122, 2022 08 18.

Artículo en Inglés | MEDLINE | ID: mdl-35862717

15.

Salmonella enterica Serovar Typhimurium Induces NAIP/NLRC4- and NLRP3/ASC-Independent, Caspase-4-Dependent Inflammasome Activation in Human Intestinal Epithelial Cells.

Naseer, Nawar; Zhang, Jenna; Bauer, Renate; Constant, David A; Nice, Timothy J; Brodsky, Igor E; Rauch, Isabella; Shin, Sunny.

Infect Immun ; 90(7): e0066321, 2022 07 21.

Artículo en Inglés | MEDLINE | ID: mdl-35678562

16.

Lipid A Variants Activate Human TLR4 and the Noncanonical Inflammasome Differently and Require the Core Oligosaccharide for Inflammasome Activation.

Alexander-Floyd, Jasmine; Bass, Antonia R; Harberts, Erin M; Grubaugh, Daniel; Buxbaum, Joseph D; Brodsky, Igor E; Ernst, Robert K; Shin, Sunny.

Infect Immun ; 90(8): e0020822, 2022 08 18.

Artículo en Inglés | MEDLINE | ID: mdl-35862709

17.

RNA helicase DHX33 puts a new twist on NLRP3 inflammasome activation.

Brodsky, Igor E.

Immunity ; 39(1): 94-6, 2013 Jul 25.

Artículo en Inglés | MEDLINE | ID: mdl-23890068

18.

Caspase-8 promotes c-Rel-dependent inflammatory cytokine expression and resistance against Toxoplasma gondii.

DeLaney, Alexandra A; Berry, Corbett T; Christian, David A; Hart, Andrew; Bjanes, Elisabet; Wynosky-Dolfi, Meghan A; Li, Xinyuan; Tummers, Bart; Udalova, Irina A; Chen, Youhai H; Hershberg, Uri; Freedman, Bruce D; Hunter, Christopher A; Brodsky, Igor E.

Proc Natl Acad Sci U S A ; 116(24): 11926-11935, 2019 06 11.

Artículo en Inglés | MEDLINE | ID: mdl-31147458

19.

Caspase-8 protein cuts a brake on immune defences.

Brodsky, Igor E.

Nature ; 587(7833): 201-203, 2020 11.

Artículo en Inglés | MEDLINE | ID: mdl-33106621

20.

The Evolving Erythrocyte: Red Blood Cells as Modulators of Innate Immunity.

Anderson, H Luke; Brodsky, Igor E; Mangalmurti, Nilam S.

J Immunol ; 201(5): 1343-1351, 2018 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-30127064

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